| ABBEVILLE AREA MEDICAL CENTER ABBEVILLE | ABBEVILLE | Critical Access Hospitals | N/A | Yes |
| AIKEN REGIONAL MEDICAL CENTER AIKEN | AIKEN | Acute Care Hospitals | 1 | Yes |
| ALLENDALE COUNTY HOSPITAL FAIRFAX | FAIRFAX | Critical Access Hospitals | N/A | Yes |
| ANMED HEALTH ANDERSON | ANDERSON | Acute Care Hospitals | 4 | Yes |
| BEAUFORT COUNTY MEMORIAL HOSPITAL BEAUFORT | BEAUFORT | Acute Care Hospitals | 3 | Yes |
| BON SECOURS-ST FRANCIS XAVIER HOSPITAL CHARLESTON | CHARLESTON | Acute Care Hospitals | 4 | Yes |
| CANNON MEMORIAL HOSPITAL PICKENS | PICKENS | Acute Care Hospitals | N/A | Yes |
| CAROLINA CTR FOR BEHAVIORAL HEALTH,THE GREER | GREER | Psychiatric | N/A | No |
| CAROLINA PINES REGIONAL MEDICAL CENTER HARTSVILLE | HARTSVILLE | Acute Care Hospitals | 3 | Yes |
| CHARLESTON VA MEDICAL CENTER CHARLESTON | CHARLESTON | Acute Care - Veterans Administration | 5 | Yes |
| CHEROKEE MEDICAL CENTER GAFFNEY | GAFFNEY | Acute Care Hospitals | 2 | Yes |
| COASTAL CAROLINA HOSPITAL HARDEEVILLE | HARDEEVILLE | Acute Care Hospitals | 4 | Yes |
| COLLETON MEDICAL CENTER WALTERBORO | WALTERBORO | Acute Care Hospitals | 2 | Yes |
| COLUMBIA SC VA MEDICAL CENTER COLUMBIA | COLUMBIA | Acute Care - Veterans Administration | 5 | Yes |
| CONWAY MEDICAL CENTER CONWAY | CONWAY | Acute Care Hospitals | 2 | Yes |
| EAST COOPER MEDICAL CENTER MOUNT PLEASANT | MOUNT PLEASANT | Acute Care Hospitals | 5 | Yes |
| EDGEFIELD COUNTY HEALTHCARE AN AFFILIATE OF SELF R EDGEFIELD | EDGEFIELD | Critical Access Hospitals | N/A | Yes |
| G WERBER BRYAN PSYCH HOSP COLUMBIA | COLUMBIA | Psychiatric | N/A | No |
| GRAND STRAND REGIONAL MEDICAL CENTER MYRTLE BEACH | MYRTLE BEACH | Acute Care Hospitals | 2 | Yes |
| HAMPTON REGIONAL MEDICAL CENTER VARNVILLE | VARNVILLE | Acute Care Hospitals | N/A | Yes |
| HILTON HEAD REGIONAL MEDICAL CENTER HILTON HEAD ISLAND | HILTON HEAD ISLAND | Acute Care Hospitals | 3 | Yes |
| KERSHAWHEALTH CAMDEN | CAMDEN | Acute Care Hospitals | 3 | Yes |
| LEXINGTON MEDICAL CENTER WEST COLUMBIA | WEST COLUMBIA | Acute Care Hospitals | 4 | Yes |
| LIGHTHOUSE BEHAVIORAL HEALTH HOSPITAL CONWAY | CONWAY | Psychiatric | N/A | Yes |
| MCLEOD HEALTH CHERAW CHERAW | CHERAW | Acute Care Hospitals | 3 | Yes |
| MCLEOD HEALTH CLARENDON MANNING | MANNING | Acute Care Hospitals | 3 | Yes |
| MCLEOD LORIS HOSPITAL LORIS | LORIS | Acute Care Hospitals | 4 | No |
| MCLEOD MEDICAL CENTER - DILLON DILLON | DILLON | Acute Care Hospitals | 3 | Yes |
| MCLEOD REGIONAL MEDICAL CENTER-PEE DEE FLORENCE | FLORENCE | Acute Care Hospitals | 3 | Yes |
| MOUNT PLEASANT HOSPITAL MOUNT PLEASANT | MOUNT PLEASANT | Acute Care Hospitals | 5 | Yes |
| MUSC HEALTH CHESTER MEDICAL CENTER CHESTER | CHESTER | Acute Care Hospitals | N/A | Yes |
| MUSC HEALTH COLUMBIA MEDICAL CENTER DOWNTOWN COLUMBIA | COLUMBIA | Acute Care Hospitals | 3 | Yes |
| MUSC HEALTH FLORENCE MEDICAL CENTER FLORENCE | FLORENCE | Acute Care Hospitals | 2 | Yes |
| MUSC HEALTH LANCASTER MEDICAL CENTER LANCASTER | LANCASTER | Acute Care Hospitals | 2 | Yes |
| MUSC HEALTH MARION MEDICAL CENTER MULLINS | MULLINS | Acute Care Hospitals | 3 | Yes |
| MUSC MEDICAL CENTER CHARLESTON | CHARLESTON | Acute Care Hospitals | 3 | Yes |
| NEWBERRY COUNTY MEMORIAL HOSPITAL NEWBERRY | NEWBERRY | Acute Care Hospitals | 3 | Yes |
| NH Beaufort Beaufort | Beaufort | Acute Care - Department of Defense | N/A | No |
| PALMETTO LOWCOUNTRY BEHAVIORAL HEALTH CHARLESTON | CHARLESTON | Psychiatric | N/A | No |
| PATRICK B HARRIS PSYCHIATRIC HOSPITAL ANDERSON | ANDERSON | Psychiatric | N/A | No |
| PELHAM MEDICAL CENTER GREER | GREER | Acute Care Hospitals | 5 | Yes |
| PIEDMONT MEDICAL CENTER ROCK HILL | ROCK HILL | Acute Care Hospitals | 2 | Yes |
| PRISMA HEALTH PATEWOOD HOSPITAL GREENVILLE | GREENVILLE | Acute Care Hospitals | 4 | No |
| PRISMA HEALTH BAPTIST COLUMBIA | COLUMBIA | Acute Care Hospitals | 5 | Yes |
| PRISMA HEALTH BAPTIST EASLEY HOSPITAL EASLEY | EASLEY | Acute Care Hospitals | 2 | Yes |
| PRISMA HEALTH BAPTIST PARKRIDGE COLUMBIA | COLUMBIA | Acute Care Hospitals | 4 | Yes |
| PRISMA HEALTH GREENVILLE MEMORIAL HOSPITAL GREENVILLE | GREENVILLE | Acute Care Hospitals | 4 | No |
| PRISMA HEALTH GREER MEMORIAL HOSPITAL SPARTANBURG | SPARTANBURG | Acute Care Hospitals | 5 | Yes |
| PRISMA HEALTH HILLCREST HOSPITAL SIMPSONVILLE | SIMPSONVILLE | Acute Care Hospitals | 4 | Yes |
| PRISMA HEALTH LAURENS COUNTY HOSPITAL CLINTON | CLINTON | Acute Care Hospitals | 2 | Yes |